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Researchers develop AI tool to map microRNA binding sites on circular RNAs

Circular RNAs (circRNAs) are loop-shaped molecules that can influence gene regulation through interactions with microRNAs (miRNAs). This matters because circRNAs can exist as different full-length isoforms, and their back-splice junction (BSJ) connects the two ends of the RNA. Treating a circular RNA like a linear transcript can therefore overlook sequence information near this junction.

Published Oct 22, 2026 · 8:45 PMOriginal source: Phys.org - latest science and technology news stories3 reads
Circular RNAs (circRNAs) are loop-shaped molecules that can influence gene regulation through interactions with microRNAs (miRNAs). This matters because circRNAs can exist as different full-length isoforms, and their back-splice junction (BSJ) connects the two ends of the RNA. Treating a circular RNA like a linear transcript can therefore overlook sequence information near this junction.
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Phys.org - latest science and technology news stories

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Original sourcePhys.org - latest science and technology news stories